Johnson & Johnson has begun the final stage of clinical trials for a coronavirus vaccine that would have an enormous benefit over its rivals: It could require only one shot as a substitute of two.

The trials, which started on Monday, would be the largest within the U.S., with plans to enroll 60,000 contributors. “It could be fabulous if we had one thing at a single dose,” stated Dr. Judith Feinberg, the vice chairwoman for analysis in drugs at West Virginia College, who was not concerned within the research.

Solely Part 3 trials, which evaluate the consequences of a vaccine with these of a placebo, can decide if a single dose is certainly efficient, Dr. Feinberg stated.

One other plus: The vaccine doesn’t must be frozen. The freezing requirement might make distribution troublesome, particularly to locations with out superior medical services.

What’s subsequent: The corporate’s chief scientific officer stated Johnson & Johnson would possibly be capable of decide by the tip of the yr if the vaccine is protected and efficient.

Listed below are the latest updates and maps of the pandemic.

In different developments:

  • Foreigners with legitimate residence permits for work, private issues and household reunions in China might be allowed to enter the nation once more with out having to use for brand new visas beginning subsequent week.

  • The Metropolitan Opera, the biggest efficiency arts group within the U.S., canceled its entire 2020-21 season, by subsequent September. The choice despatched a chilling sign that cultural life within the U.S. continues to be removed from resuming.

  • Plastic face shields do little to contain the spread of microscopic airborne particles created by such actions as speaking, singing or sneezing, in response to current analysis from Japan.


King Salman of Saudi Arabia used his first address to the United Nations General Assembly to model Iran as a power for chaos within the Center East. However there was no point out of his nation’s personal controversies.

“The Kingdom’s fingers have been prolonged to Iran in peace with a constructive and open angle over the previous many years, however to no avail,” the 85-year-old king stated in a pre-recorded video.

He accused the Iranian authorities of getting exploited worldwide efforts to comprise its nuclear actions, supporting the Houthi rebels in Yemen and focusing on Saudi oil services in missile strikes.

The king stated nothing adverse about Saudi Arabia’s personal navy function in Yemen, which the United Nations has referred to as the world’s worst humanitarian catastrophe. He expressed help for the Trump administration’s efforts within the Israeli-Palestinian battle, however shunned mentioning the opportunity of opening diplomatic ties with Israel.


Up to now, Beijing has responded to financial slowdowns by greenlighting multibillion-dollar building initiatives to shortly pump cash into the financial system. The newest concept is way much less grandiose than a superhighway or a high-speed rail line.

Elevators will be retrofitted in as many as three million older, walk-up buildings. Whereas elevators could pack a smaller financial punch, they supply a social profit for a quickly getting old inhabitants.

Officers are hoping a nationwide elevator venture might assist mitigate the financial results of the pandemic, significantly on blue-collar employees. It might present jobs to tens of thousands and thousands of still-unemployed Chinese language migrant employees.

Latin America has been devastated by the pandemic. In Mexico Metropolis, the Iztapalapa neighborhood, dwelling to the biggest produce market within the Western Hemisphere, turned the epicenter of the epicenter, registering extra deaths from the coronavirus than another a part of the capital, which is itself the middle of the nationwide disaster.

Our reporters visited Iztapalapa, where poverty, a dense population and bustling commerce mixed with devastating impact. The employees within the space have been left with little alternative. “I’ve bought nothing left,” stated one vendor who tried to remain dwelling however ran out of cash. “It’s both go on the market and face the virus or sit right here and starve.” By Could, one in every of each 10 individuals placed on a ventilator in Mexico Metropolis had been available in the market.

Belarus: Regardless of weeks of mass demonstrations towards his rule, Aleksandr Lukashenko was sworn in for a sixth term as president in a secret ceremony on Wednesday. Svetlana Tikhanovskaya, an opposition chief, denounced the ceremony as a “farсe.”

Breonna Taylor: One police officer was charged with “wanton endangerment” within the killing of the 26-year-old Black girl who was fatally shot whereas she was sleeping. Two different officers who fired photographs weren’t indicted. Protesters gathered in Louisville, Ky., the place Ms. Taylor was killed, expressing anger and disappointment. Different cities ready for protests as properly.

Ruth Bader Ginsburg: The Supreme Court docket justice was honored as a pioneer of girls’s rights throughout a ceremony on the courtroom in Washington. Her coffin was then introduced outdoors, the place she’s going to lay in repose as Americans bid farewell over the next two days.

Pakistan hearth: Eight years after the nation’s worst industrial hearth killed 264 individuals and injured 60 others at a garment manufacturing facility in Karachi, a court has sentenced two men to hang for arson. The decision fell quick for the victims’ households, who needed to see the homeowners of the manufacturing facility held to account.

Snapshot: Above, a sniffer canine in Finland educated to acknowledge the scent of the coronavirus. Just a few canines working on the Helsinki airport have been educated to detect an an infection on arriving passengers in about one minute.

What we’re watching: This desk learn of “Fast Times at Ridgemont High.” Carole Landry of the Briefings Crew writes: “The performances/readings by these stars — Brad Pitt, Jennifer Aniston, Julia Roberts, Morgan Freeman, Matthew McConaughey amongst them — are one thing to behold. It’s unimaginable enjoyable.”

Cook dinner: This corn polenta with baked eggs is featured in Melissa Clark’s “From the Pantry” collection, which began again in March to assist individuals caught at dwelling prepare dinner and bake away their pandemic anxieties. Melissa is retiring the collection and, as a parting present, listed here are five recipes that shined.

Learn: In “Let Love Rule,” Lenny Kravitz recounts the primary 25 years of his life, ending with the discharge of his debut album in 1989. The story he tells isn’t about stardom, however concerning the influences that impressed his distinctive musical hybrid of soul and traditional rock.

Watch: On the lookout for a couple of contemporary streaming choices? Right here’s our listing of 10 unusual movies for unusual times.

Being bored at dwelling is just not an choice with our full At Home collection of ideas on what to learn, prepare dinner, watch and do.

Underneath worldwide strain to do extra to deal with international warming, President Xi Jinping has made a shock dedication to drastically scale back emissions — however he supplied few particulars. Steven Lee Myers, our Beijing bureau chief, took a better have a look at what it means.

Mr. Xi’s pledge is a tectonic shift in coverage, not but follow. Underneath the Paris local weather deal, China pledged that its emissions would peak round 2030. Mr. Xi promised on Tuesday to maneuver up that timetable, although he didn’t present specifics. The larger shock, analysts stated, was his pledge to achieve carbon neutrality — which means China’s internet carbon emissions will attain zero — by 2060. China now could be the most important producer of the world’s emissions, pumping out 28 % of the worldwide complete.

China would want to reverse current emissions tendencies. Analysts have warned about worrisome tendencies within the nation. Coal consumption, which had declined from 2013 to 2017, started to rise once more lately as the federal government sought to stimulate progress.

After the shutdown in the course of the pandemic, China’s financial system roared again. Analysis has proven that by Could, carbon dioxide emissions have been 4 % larger than the yr earlier than. China additionally granted extra building permits for coal-fired energy vegetation within the first six months of 2020 than it had every year in 2018 and 2019.

The affect might have an effect on all 1.4 billion individuals in China. Li Shuo, a coverage adviser for Greenpeace China, stated the pledge required an entire transformation of the Chinese language financial system.

“Give it some thought: The way in which we eat, the best way we eat vitality, the best way we produce our meals, the best way we commute to work will must be fully rearranged,” he stated. Preserving the Communist Celebration’s energy stays Mr. Xi’s first precedence, however air pollution and different environmental threats are more and more seen as threats to the get together’s standing.


That’s it for this briefing. See you subsequent time.

— Melina


Thanks
To Melissa Clark for the recipe, and to Theodore Kim and Jahaan Singh for the remainder of the break from the information. You may attain the workforce at briefing@nytimes.com.

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